Browsing by Subject "Bayes theorem"
Now showing items 1-4 of 4
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Article
A method for meta-analysis of case-control genetic association studies using logistic regression
(2007)We propose here a simple and robust approach for meta-analysis of molecular association studies. Making use of the binary structure of the data, and by treating the genotypes as independent variables in a logistic regression, ...
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Article
Mixed-effects poisson regression models for meta-analysis of follow-up studies with constant or varying durations
(2009)We present a framework for meta-analysis of follow-up studies with constant or varying duration using the binary nature of the data directly. We use a generalized linear mixed model framework with the Poisson likelihood ...
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Article
Population pharmacokinetic and dynamic analysis of the topoisomerase I inhibitor lurtotecan in phase II studies
(2002)Population pharmacokinetic-dynamic analysis was prospectively integrated in a broad phase II program of lurtotecan (GI147211), a novel camptothecin derived topoisomerase I inhibitor, to determine the population pharmacokinetic ...